Biologics Manufacturing Solutions from Honeywell

This description pertains to Biologics Manufacturing.

For Solutions for Clinical Manufacturing, Ethical Drug Manufacturing, Over-the-counter Drug Manufacturing, Fine Chemicals Manufacturing, Medical Devices Manufacturing, or Regulated Consumer Packaged Goods Manufacturing, click on the appropriate left-hand sidebar topics.

The manufacturing of biologic materials is a huge opportunity and an equally huge challenge for biotech companies. Once a new biologic product is approved for general use, the demand for the product is extreme, and the need for production capacity suddenly shoots through the roof! Yet, processes are lengthy, complex and subject to variability that can present daunting problems to manufacturing.
With skyrocketing potential for sales, the cost of manufacturing a batch of biologic product will be insignificant compared to the revenue lost due to shortages of the product. To meet such demand, biologic companies must improve yields in existing plants, create new production capacity, or contract out production.
With excess capacity in short supply, creating more capacity through new or renovation construction is often the only alternative. In addition to tanks, pipes, pumps and heaters, the builders recognize that management and control systems for the new facilities must be agile, flexible and capable of managing the complex processes associated with biologics, if the return on investment is to be maximized. Honeywell offers the products and solutions required for these new, flexible biologics manufacturing facilities.

With Honeywell, you can take control of processes and the environment in your biologics manufacturing facility. Our biologics solutions integrate best practices in such key areas as process control, environmental control and validation—literally every cost center in the plant. These solutions enable you to link complex biologic process automation systems to higher-level platforms such as Enterprise Resource Planning (ERP) or Laboratory Information Systems (LIMS), leveraging information and interoperability to boost performance and drive down costs.

Honeywell solutions minimize the risks associated with maintaining compliance—and reduce the high cost of being late to market. Our automation solutions allow you to meet current and emerging regulatory requirements, such as OSHA, FDA Current Good Manufacturing Practices (cGMP), 21 CFR Part 11, and GAMP, as well as internal quality control documentation and standards.

Implementation of Honeywell's integrated solutions for biologics manufacturing provides the agility needed to stay ahead of the competition and to respond quickly to changing production demands. Honeywell solutions also help you reduce the costs associated with maintenance and unplanned equipment failures that cause lost production time.

Honeywell's next-generation Process Knowledge System™, Experion PKS™, incorporates the latest plant automation technologies, including FOUNDATION™ fieldbus, HMIWeb—Honeywell's patented human-machine interface technology, Digital Video Manager (DVM) and @sset MAX Alert Manager to protect your plant assets. The Experion PKS open, scalable process and environmental control platform supports today's flexible manufacturing strategies. Process Knowledge Solutions™ address the entire spectrum of your automation and business requirements.

Honeywell's Facility Management Solutions provide the information needed to make crucial decisions quickly. At the core of these solutions is our Enterprise Building Integrator (EBI) facility management system. This fully-integrated control platform pulls together all core building systems and integrates information from many different enterprise subsystems, from industrial manufacturing and process automation, to financial records, environmental controls and data warehouses.

Our industry-best MES solution (POMS MES) allows you to manage every step of the production life cycle from materials receipt to product shipment. POMS MES manages execution decisions and information during the biologic processes of planning/campaign management, inoculum prep, cell prep and growth, purification, recovery and finished product preparation.. POMS MES ensures your manufacturing operations are capable of delivering on your enterprise's e-business supply chain commitments.

Honeywell's eSpec provides an electronic specification solution for modeling complex biologic processes and a tool for deployment of the specifications and procedures to the process floor. This system organizes and automates the process of delivering new biological healthcare-related products from concept to commercial manufacturing. eSpec manages all data relating to materials, equipment, recipes and procedures,. eSpec forms the bridges between research, production planning, manufacturing and quality control to enable rapid deployment of product data in a regulated environment.

By integrating best practices with quality and regulatory compliance, Honeywell Biologics Solutions give you the means to minimize risk, increase throughput, enforce proper execution of complex processes, and streamline production costs while focusing on "Critical to Quality" factors associated with biologics manufacturing.

The left-hand sidebar on this page lists Honeywell products that are particularly appropriate for use in Biologics Manufacturing. Please click on those products of interest for more detailed information.